Tuesday, October 29, 2019

Biochemistry (Henderson-Hasselbalch Relationships)

Calculate the pH of mixture of 0.1 M acetic acid (CH3COOH) and 0.2 M sodium acetate (CH3COO-).(The pH acetic acid is 4.76).
                                     [deprotonated]
           pH = pKa + log ----------------  
                                       [protonated]


           CH3COOHCH3COO- + H+

                                     [CH3COO-]
           pH = pKa + log ----------------  
                                     [CH3COOH]

                                     [0.2]
           pH = pKa + log ------
                                     [0.1]
          pH = 4.76 + 0.301
          pH = 5.06

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