Tuesday, October 29, 2019

Fibrous Protein Vs Globular Protein

The comparison between fibrous and globular protein.


Fibrous Protein
Characteristic
Globular Protein
Long and narrow
Shape
Globular and spherical
Repetitive amino acid
Acid Sequence
Irregular amino acid
Less sensitive to change in pH and temperature
Durability
Sensitive to change in pH and temperature
Weak  interaction
Interaction
Strong interaction
Insoluble in water, acid and bases
Solubility
Soluble in water, acid and bases
Forming structure
Involvement
Metabolic reaction
Secondary structure
Type of Protein
Tertiary structure
Collagen, keratin and myosin
Example
Myoglobin, haemoglobin and hormone

Biochemistry (Henderson-Hasselbalch Relationships)

Calculate the pH of mixture of 0.1 M acetic acid (CH3COOH) and 0.2 M sodium acetate (CH3COO-).(The pH acetic acid is 4.76).
                                     [deprotonated]
           pH = pKa + log ----------------  
                                       [protonated]


           CH3COOHCH3COO- + H+

                                     [CH3COO-]
           pH = pKa + log ----------------  
                                     [CH3COOH]

                                     [0.2]
           pH = pKa + log ------
                                     [0.1]
          pH = 4.76 + 0.301
          pH = 5.06